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Yuan, C., et al

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The first goal is to stabilize the patient : identify urgent safety risks, continue necessary medication when the patient is severely unstable, test the relevant nutrient and biochemical patterns, begin targeted correction, and then reassess whether the medication choice and dose still make sense

J Exp Med (2005) 202(10):131925

However, it can be a symptom of a dangerous or even life-threatening condition, such as stroke, aneurysm, hemorrhage, or other cardiovascular emergency

Given functional redundancy whereby multiple bacterial taxa generate identical uremic toxin precursors, serum metabolite quantification (IS, pCS) suffices for therapeutic surveillance, reserving microbiome profiling for baseline characterization (278)