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Cholangiocyte organoid culture For cholangiocyte organoid cultures, EpCAM-positive cholangiocytes were mixed with Matrigel growth factor reduced (Matrigel, Corning) or Cultrex basement membrane extract 2 (BME2) (Cultrex-RGF basement membrane extract type 2, BME2 (AMSBIO) at 50,000 cells per 50 l in each well of a 24-well plate and cultured at 37 C and 5% CO 2 in h-CholOrg EM medium as described in refs

Physiologically, IL-6 is a pleiotropic cytokine that regulates a wide array of homeostatic processes, including immune surveillance, hematopoiesis, metabolism, and tissue regeneration

Open communication with healthcare providers about supplement and peptide use supports safer protocols even when providers lack specific peptide expertise

Procalcitonin-guided antibiotic therapy in patients with fever in a general emergency department population: a multicentre non-inferiority randomized clinical trial (HiTEMP study)