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found that that with both SEV and ISO, the increase in PARP was short lived, elevating at 4 h post exposure, but not detectable by 24 h post exposure, potentially indicating that this increase is an acute response (143)

These results align well with experimental data [99]

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Cell-based therapy includes adoptive T-cell therapy, Granulocyte transfusion, CAR-Chimeric antigen receptor T-cell therapy, and mAbs (monoclonal antibodies) ( Figure 3 )