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The Nrf2 content is significantly higher in hyperoxic mice than in normal oxygen-treated mice

Li T, Wang Y, Zhou D

doi: 10.1016/j.redox.2021.102065 29 SonJLyssiotisCAYingHWangXHuaSLigorioMet al

Further, controlled clinical studies simulating NSW provide causal evidence that melatonin secretion diminishes rapidly upon night work exposure and remains suppressed with continued circadian disruption 183

Glabska et al., 2019)

NCOA4-mediated ferritinophagy, which is responsible for degrading key iron storage proteins to release free iron, can be attenuated by NCOA4 knockdown to alleviate ferroptosis in intestinal epithelial cells induced by IR, thereby reducing intestinal mucosal injury [18]