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The mass spectrometer coupled to UPLC was a XEVO-TQS (Waters Corporation, Milford, MA, USA) used with the following conditions: polarity API+, corona needle discharge electric current (uA): 0.54

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Within the complex, p53 TAD2 residues 47 to 54 displayed increased rigidity upon binding and consistently maintain an -helical conformation throughout the MD calculations (Fig

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International Journal of Pharmaceutical Sciences Review and Research