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In addition to GLS inhibitors, strategies targeting the conversion of glutamate into -ketoglutarate, such as GDH inhibitors and aminotransferase inhibitors, have also been evaluated in preclinical models of breast cancer and neuroblastoma [103-105]

identified that, uniquely among dopamine precursors or metabolic components, dopamine itself induces cellular iron accumulation during its metabolism (127)

doi: 10.1530/REP-17-0342 38

Eid T, Lee TW, Patrylo P, Zaveri HP

The three formulas the calculator uses: Concentration (mg/mL) = vial mg bacteriostatic water mL Units to draw = (target mcg (vial mg 1000)) water mL 100 Doses per vial = (vial mg 1000) target mcg, rounded down A 5 mg vial reconstituted with 2 mL of bacteriostatic water is 2.5 mg/mL, or 25 mcg per unit

Keeping Hormones in Check The protection that glutathione offers to our cells extends to those involved in hormonal regulation