According to that stimulating opportunities, we decided to investigate, by means of state-of-the-art DFT calculations and Baders Quantum Theory of Atoms In Molecules analyses, two families of chelating agents (catechols and salicylic acids with different substituents, Fig.1 and Fig.2) which are well known to show high affinity toward Al(III) 4 The goal was to set-up a theoretical approach that fits well with the available experimental data, and then to apply it against promising metal chelators, in order to characterize the nature of their interaction with Al(III) and to unveil the effect of different substituents toward the modulation of the binding affinity
Herbs and herbal extracts with well-described anti-inflammatory, vascular-stabilizing, antimicrobial, and microbiome-balancing effects may have anti-rosacea benefits, including 82,83 : Curcumin (from turmeric, Curcuma longa ) Green tea ( Camellia sinensis ) Resveratrol (from red grapes, red wine, and peanuts) Feverfew ( Tanacetum parthenium ) Chamomile ( Matricaria recutita ) Lavender ( Lavendula angustifolia ) Oat ( Avena sativa ) In one randomized controlled trial, 30 subjects with rosacea received twice-daily treatment with 2,000 mg of turmeric, an Ayuvedic multi-herb combination containing turmeric, anantamul ( Hemidesmus indicus ), manjistha ( Rubia cordifolia ), neem ( Azadirachta indica ), gotu kola ( Centella asiatica ), guduchi ( Tinospora cordifolia ), bhumyamalaki ( Phyllanthus amarus ), amalaki ( Phyllanthus emblica ), and licorice ( Glycyrrhiza glabra ), or placebo for four weeks
Cell 5 : 897904 Watanabe M, Osada J, Aratani Y, Kluckman K, Reddick R, Malinow MR and Maeda N (1995) Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia
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BPC-157, or Body Protection Compound-157, is a synthetic peptide with 15 amino acids
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