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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

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When a full course produces nothing noticeable, additional courses may or may not change the outcome there's no data to guide that decision

GHK-Cu has demonstrated anti-inflammatory properties in published research, and tolerability is generally favorable compared to retinoids or high-concentration alpha hydroxy acids