Neurogastroenterol Motil 28:14091418 Wasilewski A, Lewandowska U, Mosinska P et al (2017) Cannabinoid receptor type 1 and -opioid receptor polymorphisms are associated with cyclic vomiting syndrome
So thats why they call it the new frontier because its really a new science

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Isr J Chem 60:180194
Abstract Background We recently reported that supplementing glycine to soybean meal-based diets is necessary for the optimum growth of 5- to 40-g (Phase-I) and 110- to 240-g (Phase-II) hybrid striped bass (HSB), as well as their intestinal health
This knowledge has paved the way for the development of personalized medicine approaches that target cancer-initiating cells, offering new hope for improved treatment outcomes [524]