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Pro-inflammatory factors such as IFN- weaken GSH synthesis by downregulating the cystine transporter SLC7A11, thereby enhancing ferroptosis sensitivity (Wang et al., 2020) (209)

It also enhanced antioxidant defenses by increasing SOD, catalase, and GSH activities, while reducing neuroinflammation by lowering IL-1, TNF, and IL-6 levels

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If left un-neutralized, free radicals accumulate in the body and cause oxidative stress, a type of cell damage that can harm DNA, proteins, and other vital molecules

Moreover, the researchers commented that Ipamorelin appears to be the first GHS-R agonist with a selectivity for GH release similar to that displayed by GHRH

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