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Sengupta S (ed.)

Cobalt naphthenate used in the polyester resin and plastics manufacturing industries can also cause an allergic contact dermatitis, but this may not be detected by the standard patch test with cobalt chloride

If patients are to start NASCOBAL before having tolerated cyanocobalamin parenterally, consider administering an intradermal test dose of parenteral vitamin B12 to patients suspected of cyanocobalamin hypersensitivity [see Dosage and Administration (2.1)]

Pernicious anemia is an autoimmune disease that attacks and potentially destroys gut cells so that intrinsic factor is not present, which is crucial for vitamin B12 to be absorbed