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2010;5(9):e12679

Withaferin A (WA) has been found to not only inhibit the activity of GPX4 in neuroblastoma but also activate heme oxygenase-1 to increase intracellular Fe 3+ concentration, thereby inducing ferroptosis in neuroblastoma [136]

AS is the prototypic form of SpA with potentially most severe outcome and is characterized by predominantly axial skeletal symptoms and radiographic evidence of sacroiliitis, as defined by the modified New York (mNY)

The stem samples were placed into 2.0 mL centrifuge tubes containing 5 mm shaking beads and immediately frozen in liquid nitrogen

SIRT1, a redox-sensitive NAD-dependent deacetylase, normally exerts cytoprotective effects by inhibiting NF-B, promoting Nrf2 activation and maintaining mitochondrial function