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doi: 10.1021/acs.jmedchem.7b01422

Urinary methylmalonic acid as an indicator of early vitamin B12 deficiency and its role in polyneuropathy in type 2 diabetes

However, there are cases where patients experience ongoing deterioration in their developmental status, even after initiating treatment with folic acid and various antiseizure medications at the age of 1 year, with seizures reaching more than 30 times per day [110]