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doi: 10.7759/cureus.38398 4 AggeletopoulouI.MarangosM.AssimakopoulosS

As the suprachiasmatic nuclei, in the brain, progressively synchronize with environmental cues, key circadian outputs, such as core body temperature, cortisol, and melatonin secretion, begin to exhibit defined periods, phases, and amplitudes

These SDF files were converted into the mol2 format using Open Babel software 111

Zepbound also became the first prescription medication approved by the FDA to treat moderate-to-severe obstructive sleep apnea in adults with obesity, expanding its clinical use beyond weight management alone

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