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51 The prevalence of CTCs in GBM exceeds 75%, with their levels directly reflecting the tumor burden and therapeutic response

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It appears the initial reduction in intensity is due to displacement of YOYO-1 via direct competitive DNA binding by the complex, while recovery at 5 and 10 M occurs due to non-competitive binding events that cause the DNA to contract, increasing the YOYO-1 density per pixel

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