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It does this by donating an electron to free radicals, which stabilizes them and prevents them from causing damage to cells and tissues

HG-induced iron overload generates hydroxyl radicals, causing mitochondrial membrane potential (MMP) depolarization, mtDNA damage, and dysfunction ( 3.3.5 Antioxidant proteins as potential therapeutic targets for ferroptosis in DN Ferroptosis in DN is governed by a core network of antioxidant proteins, with Nrf2 as the master transcriptional regulator

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Images were pseudocolored with the ratio of fluorescence excited at 407 nm and 482 nm

This refluxing step was repeated twice, followed by centrifugation, and washing with ethanol

As a dietary supplement, NAC is therefore a highly attractive alternative to L-Cysteine