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piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

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Its structure features two key modifications that set it apart: An arginine substitution at the third position A 13-amino acid extension at the N-terminus This unique molecular architecture results in a more stable compound with a molecular weight of approximately 9.1 kDa, specifically designed to optimize its performance within the human body

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Schapira and Tolosa, 2010