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The vast majority of these NHRs appear to be derived from an ancestor related to Hepatocyte Nuclear Receptor 4 (HNF4

doi: 10.1080/07315724.1999.10718830

Thus, this phenomenon is unclear and needs further investigation

262,263 Additionally, substituting dietary SFAs with monounsaturated fatty acids improves nerve function in HFD mice without significantly altering plasma metabolic profiles, suggesting that dietary fats influence neuropathy development

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