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SKU: 89408477427
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Oncol, 2012, 7, 137142

Kathleen L

The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD +

Together, one might conclude that action of MPO in innate host defense might be essential only in case of serious fungal infections and/or in situations where exposure of pathogens overwhelms the capacity of other host defense mechanisms

Mechanistically, overexpression of CD36 increases lipid peroxidation, mitochondrial ROS production, the labile iron pool, and especially Fe 2+ content