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Furthermore, a retrospective study illustrated that patients with glioma and depression are associated with shorter overall survival (OS) when compared with patients without depression, with median survival times of 7 and 11 months, respectively

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While the haem biosynthesis and degradation pathway has already been demonstrated to be synthetic lethal in FH-deficient cells, the role of GSH metabolism in FH-deficient cells has not been investigated before and required further investigation

Notably, AC-like neoplastic populations were enriched in programs involved in oxidative stress responses, including taurine/hypotaurine metabolism and glutathione peroxidase activity

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Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor