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Targeting the JAK-STAT signaling pathway can alleviate chronic inflammation, improve immune cell function, and delay the onset of aging-related phenotypes

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The cause was the lack of ATP, which led to a decrease in the level of GSH because of the inhibition of its synthesis and, probably, due to a decrease in the NADPH level required for glutathione (GSSG) reduction and protein deglutathionylation

(3) the reduced form of vitamin E (-tocopherol) 13,14

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