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Following intercellular transfer, neurons metabolize the astrocyte-derived glutamine to replenish both glutamate and GABA pools, thereby sustaining neurotransmitter homeostasis and excitatory-inhibitory balance (Andersen 2025)

These mutations cause dysfunction of sterol 27-hydroxylase enzyme, resulting in incomplete oxidation of the cholesterol side chain

Notably, the significantly enriched pathways in the skin included the FOXO signaling pathway, pyrimidine metabolism, linoleic acid metabolism, and arginine and proline metabolism (Fig

Some individuals may experience mild gastrointestinal discomfort or bloating

44 described a case of statin-induced cholestasis in a 72-year-old man who had been treated with atorvastatin and developed nausea, jaundice, and scleral icterus with marked elevations of bilirubin (total bilirubin 22 mg/dL) and ALP (four times the ULN) and only marginal increases of aminotransferases

MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma