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Crosslinkable polyesters include those known in the art and described in US Pub

In laboratory peptide signaling studies, DAC-linked formats are generally described as having a longer observable activity window, while non-DAC formats are discussed in relation to shorter pulse-oriented signaling behavior

While the outcome is unknown it is promising that the FDA is willing to have a dialogue with the stakeholders in this new and rising drug class, and are willing to look more closely as the safety and efficacy of many of these peptides

Clarifying the causal relevance of these signatures will require longitudinal human studies and targeted epigenetic manipulation in defined neural circuits

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International Journal of Advances in Medicine