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However, current evidence is primarily derived from in vitro models or animal studies, and often relies on indirect indicators such as protein expression changes (e.g., LC3-II, Beclin-1)

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In addition, a dose-dependent PDT-mediated increase in cytotoxicity was observed for 6a and 6b in two pancreatic cancer cell lines (BXPC-3 and MIA PaCa-2), and 6a was proved to be more potent than 6b in the MIA PaCa-2 cell line ( A common strategy to improve the stability and targeting Cy7 is through structural modification and binding with specific ligands, such as TPP and hyaluronic acid (HA)

Oral glutathione is poorly absorbed because stomach acid breaks the peptide bonds

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