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Description

One example is that reported in a study by Paez-Ribes et al

Int J Mol Sci (2020) 21(22):8793

doi: 10.1097/MCO.0000000000000691, 89

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In the asymptomatic phase (4 months of age), the PINK1 knockout rat model has already exhibited mitochondrial dysfunction-related changes such as metabolic abnormalities, complex I activity-related alterations, and changes in oxygen consumption (196)