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Multimodal smart systems reprogramme macrophages and remove urate to treat gouty arthritis

An extreme case was the ketone-bearing MF5 which led to no conversion, whereas the acetal-protected version thereof (MF6) led to 56% yield

PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage

Elmslie JL, Porter RJ, Joyce PR, Hunt PJ, Mann JI

Beyond their role in general metabolism, emerging evidence suggests that amino acid metabolic reprogramming plays a crucial role in the pathogenesis of IPF

The signals were detected using the Amersham ImageQuant 800 imaging system (Cytiva, Sweden)