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Obesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer

However among patients with lean NAFLD, A1AT Pi*MZ was not significantly associated with an increased risk of hepatic events (OR 1.1, 0.75-1.6, p=0.59)

Xiong G, Huang D, Lu L, et al

Introduction and review of clinical and laboratory indications

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA (2019) Mitophagy inhibits amyloid- and tau pathology and reverses cognitive deficits in models of Alzheimers disease

found that dexmedetomidine could activate 2A adrenoceptors on astrocytes but not microglia to decrease proinflammatory factors in the brain, preserve BBB integrity, and enhance learning and memory performance by activating 2A adrenoceptors on astrocytes in septic mice (Mei et al., 2021) ( Figure 2 )