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10.1590/s0100-46702009000100003 187 VoonF

6 Monoclonal antibodies directed against this protein are associated with multiple mechanisms of action that can attack the multiple myeloma cells, and two agents have been approved in the treatment of patients with multiple myeloma: daratumumab and isatuximab

IGF-1 LR3 binding to IGFBPs is reduced by roughly three orders of magnitude

The majority of research-grade peptides clear systemically within 57 half-lives, but downstream signaling effects and extracellular matrix binding may extend biological activity beyond serum detection limits

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