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Description

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

1 2 Dodd S, Dean O, Copolov DL, Malhi GS, Berk M (December 2008)

Another approach is to disrupt protein-protein interaction between DNMTs and their protein counterparts rather than targeting their catalytic pockets (90)

Neoplastic transformation of the peribiliary stem cell niche in cholangiocarcinoma arisen in primary sclerosing cholangitis

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