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In astrocytes, LPS also increases NFB-mediated transcription of pro-inflammatory cytokines, including TNF, IL-1, iNOS and cyclooxygenase-2 (COX2) (Bobermin et al., 2020)

Silencing of RRM1 likewise inhibited the accumulation of lipid peroxides in response to erastin2 treatment, as determined by confocal imaging of the lipid peroxidation probe C11-BODIPY 581/591, whose oxidation is highly correlated with the onset of ferroptosis (Dixon et al, 2012

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