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First, the clinical effectiveness of antipsychotic drugs is directly related to their affinity for DA receptors [55]

Following the clathrin-mediated internalization, the GRPR is separated from the endosome and recycles back to the cell membrane rapidly, where it can be activated again (Slice et al., 1998)

10.1097/00001756-199704140-00022 17 KhairallahM.KhairallahR.YoungM

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Some authors question its use [21] while others favour it, although the methodological limitations of the evidence they provide means no firm conclusions can be drawn