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EMT and the tumor cells microenvironment (TME) are linked through the FBXW7-ZEB2 axis to promote colorectal CSC formation and chemoresistance [40]

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Acknowledgments The authors would like to thank the Core Facilities Sharing Platform for Life and Environment Sciences of Shandong University, including Cheng-Jia Zhang and Nan-Nan Dong for providing the bacteriological incubator and Zhi-Feng Li for RT-qPCR instruction

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A prior study has suggested that LC is involved in inflammatory pathway mediation by reducing inflammatory cytokines (46)

Prevalence of vitiligo among type 2 diabetic patients in an Iranian population