what's the difference between melanotan 1 and 2

what's the difference between melanotan 1 and 2 Evolution of Melanotan 1 vs Melanotan 2:

Name: what's the difference between melanotan 1 and 2 Evolution of Melanotan 1 vs Melanotan 2:
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Esculetin (12 g/ml) also inhibits the expression of inducible isoform of NO synthase (iNOS), cyclooxygenase 2 (COX-2), TNF- and IL-1 in LPS-induced RAW 264.7 cells by inhibiting the NF-B signaling pathway (73)

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For non-integrative Sendai virus mediated reprogramming, we used the CytoTune-iPS 2.0 Sendai Reprogramming Kit (Life Technologies) containing polycistronic Klf4Oct3/4Sox2, cMyc, and Klf4, according to the manufactures instructions for feeder free derivation

Liver Int 2022;42:9-15

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Animal studies have reported various effects, including potential lifespan extension in rodent models and improvements in certain biomarkers associated with aging