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A randomized, open-label, multiple-dose, parallel-arm, pivotal study to evaluate the safety, tolerability, and pharmacokinetics of aripiprazole 2-month long-acting injectable in adults with schizophrenia or bipolar I disorder

Copper delivery through the skin has many potential applications and thus is widely studied, including the evaluation of the penetration ability of copper peptides 30 , biocompatibility of copper containing IUD 1 , the enhancement of skin absorption through copper-containing nanoparticles 10 and microneedle-mediated delivery 5

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5 Conclusion Preventing DDIs related to oral anticoagulants is of major relevance for ensuring patient safety

Though the gene encoding DSIP has not been identified and its receptor remains unknown, emerging studies indicate that its activity may be mediated through NMDA receptors in the brain and 1-adrenergic pathways in peripheral tissues