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Some factors associated with low intrinsic factor include: Being over 60 Northern European or Scandinavian ancestry A family history of intrinsic factor issues Autoimmune conditions such as Type 1 diabetes Surgeries where part of the stomach has been removed Other factors that may affect intrinsic factor or overall B12 absorption include: Stomach lining inflammation Conditions affecting the small intestine Long-term use of antacids Disruption of gut flora Certain gastrointestinal infections If any of the above apply, holding B12 sublingually for 30 seconds before swallowing may be helpful

Fasting protocols are essential for maximum benefit

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In others, it suppresses cancer progression

PMID: 28240361

Besides, a comparative study found that as a therapeutic agent for alleviating oxidative stress damage or renal oxidative injury, MitoTEMPO demonstrates greater potential and safety compared to SKQ1 [223]