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Elevated levels often mean the body is under toxic or oxidative load which can occur with heavy metals, environmental exposures, or poor detoxification capacity

Additionally, this clinical trial holds great promise because it has been recently shown that cerebellar modulation via intermittent theta-burst stimulation improves gait and balance in stroke patients, possibly through neuroplasticity mechanisms (ClinicalTrials.gov Identifier: NCT03456362 [124])

Oral Supplements: High-dose Vitamin D, Iron tablets, Vitamin B complex, and calcium are commonly prescribed

On the other hand, reduction in the number of activated Kupffer cells and inflammatory cell infiltration, diminished sinusoidal dilatation and congestion in addition to mild vacuolar degeneration in hepatocytes were observed in the MTX + WPC group (Fig

Kidneys are another potential target of supplement-induced toxicity, owing to the facts that many herbal constituents and potent nutraceuticals undergo renal excretion or may modulate renal haemodynamics and tubular functions (214)