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In mice, shed IECs have been shown to persist for several hours, promoting the expression of antimicrobial genes at the tips of villi and helping to control the makeup of the gut microbiota (219).The rate of senescent epithelial monolayer cell clearance and the growth of stem cells in the crypts are both correlated with the shedding and renewal of IECs (220, 221)

2018;13:e0191194

[0417] Like PE, diphtheria toxin (DT) kills cells by ADP-ribosylating elongation factor 2 thereby inhibiting protein synthesis

The influenza vaccine remains the most important tool to prevent serious illness or death from flu

28 January 2021

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