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Update on neuroprotection after traumatic brain injury

Pharmacol Res 74: 3444

Emerging evidence indicates that ferroptosis modulates immune cell function, while immune cells regulate ferroptosiscreating a self-perpetuating cycle of inflammation and tissue damage

(PDF 83 kb) Figure S2

This lack of synergy indicates that STEAP1 and DMT1 operate downstream of PrP in the pathway that directs Cu from endosomes to intracellular toxicity sites