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Discomfort from mild local reactions is managed by applying a cold compress to the shoulder area around the injection site and using over-the-counter pain relievers such as acetaminophen or ibuprofen as necessary

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In this DATATOP study (Deprenyl and Tocopherol Antioxidant Therapy of Parkinsons) [82] the Parkinsons Study Group evaluated 2,000 IU of tocopherol and 10 mg of deprenyl per day in 800 subjects with early PD