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Such solutions should be discarded rather than used, as activity is likely compromised

This means that they can pass a normal gene, carrier state or disease state to their children, depending on the genetics of their partner

Bertrand, E

It was effectively applied either immediately (prophylactically) after paracetamol challenge or (therapeutically) administered after a 3 h period had elapsed (note, the maximum depletion of hepatic glutathione occurred 3 h after acute paracetamol dosing (37))