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However, commonly used ferroptosis modulators are often associated with significant side effects, including pulmonary toxicity (Parry et al., 2002), liver damage, and neurotoxic effects (Zaafar et al., 2024)

Phosphorylation-Dependent Regulation of T-Cell Activation by PAG/Cbp, a Lipid Raft-Associated Transmembrane Adaptor

After each cohort, safety and tolerability data are carefully reviewed before any escalation to the next dose level is considered

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Lapenna D, Pierdomenico SD, Ciofani G, et al

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