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JC virus is an etiologic agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease

In hepatocellular carcinoma models, this approach produced high levels of ONOO inside mitochondria, causing irreversible damage to the ETC, inhibiting ATP production, and triggering cancer cell death, which significantly reduced tumor volume (134)

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Animal studies have also shown that copper chelators modulate the early events of Htt misfolding and reduce neurotoxicity in the Drosophila HD model (90,113,114)

4.5 Effects of exercise combined with tDCS on cognitive function in elderly individuals with different types of cognitive impairment Subgroup analysis stratified by cognitive status categorized participants into a cognitive impairment group and a non-cognitive impairment group

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