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Absorption of vitamin b12 The guts ability to absorb vitamin b12 can be reduced by a number of factors, these include Some conditions of the digestive system, such as Chrons disease

A 2014 study of 200 patients with periorbital hyperpigmentation found that 50% had iron deficiency anemia and many of those patients reported that their dark circles improved significantly once the anemia was treated

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Some clinical trials have examined the effects of vitamin D on migraine in conjunction with other therapies

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