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siGAPDH) = 0.169

Additionally, some bacterial metabolites can act as signaling molecules which induce the synthesis and release of neurotransmitters by enteroendocrine cells (Yano et al., 2015)

The induction of colitis with TNBS caused elevated levels of pathological scores via activation of NF-B translocation in the colon epithelium which has been reversed by treatment with d-limonene [109]

However, further work in maintaining antioxidant stability and formulation for daily use, as well as studies in larger species, is needed

Acknowledgements This research was funded by NIH grants (U01 AI073755 and U19 AI181960 to M.S.D., J.E.C

Immune function Growth hormone plays a role in immune system regulation