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Therapeutic potential and mechanism of Chinese herbal medicines in treating fibrotic liver disease

Additionally, the BCL2 family promotes the transcription of nuclear factor erythroid 2-related factor 2, which initiates an antioxidant response that reduces ROS levels, enhances cellular protection and growth, and contributes to tumor progression and drug resistance (58)

Breast Cancer Res (2011) 13(2):206

Decreased steric hindrance and increased hydrophobicity are possible reasons for the improved catalytic efficiency of S586A

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The chronic use of any of these medications has the potential to cause complications related to vitamin B12 deficiency, which includes impaired DNA synthesis, impaired cell division, hematopoiesis, hyperhomocysteinemia, and metabolism of odd-chain fatty acids that is necessary in preventing demyelination of nerves