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Due to somewhat poorer quality of the electron density map for 1a S -IN-8 or for 1a R -IN-8 the binding poses had to be decided by generating the different alternatives and analyzing the peaks in the Fo-Fc density maps

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65,66 Notably, molecular changes exhibited by non-proliferative reactive astrocytes can be fully reversible over time after single exposures for example to neuroinflammation caused by LPS