You should contact your GP if: You have been found to have elevated B12 levels on blood tests, particularly if levels exceed 1000 ng/L (approximately 740 pmol/L, though laboratory reference ranges vary) and you are not taking high-dose supplements You develop new symptoms after starting B12 supplementation, including persistent skin rashes, significant gastrointestinal disturbance, or unexplained symptoms You have underlying liver disease, kidney problems, or blood disorders and are considering B12 supplementation You are taking B12 supplements without medical supervision and have not had your levels checked, particularly if taking doses exceeding 2000 micrograms daily You experience symptoms that might indicate underlying disease, such as unexplained weight loss, persistent fatigue, jaundice, or abdominal swelling Call 999 or go to A&E if you develop severe allergic reactions following B12 injections, including difficulty breathing, facial swelling, or widespread rash, as these may indicate anaphylaxis, though this is extremely rare
Below, we outline some of the most notable preclinical and clinical studies related to AOD-9604's effects: In a 12-week clinical trial, participants administered 1mg/daily AOD-9604 experienced an average weight loss of 5.72lb, while the placebo group shed only 1.76lb
B12 injections should be used thoughtfully, with guidance from professionals who understand your health history, your goals, and the bigger picture of sustainable weight loss
Are B12 shots safe and what are the side effects
Here is the daily recommended allowance of vitamin B12 for different age groups of individuals:
Your doctor will also aim to understand the underlying cause of your deficiency, which dictates the most appropriate treatment
