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We exploited this large RNA Seq dataset to develop specific hypotheses concerning the regulation of ferroptosis by the p53 pathway

Non-pharmacological interventions include medication adjustment

A: investigation and methodology

However, this safety mechanism was found to fail under Zinc-deficient conditions, wherein these signaling proteins degrade, leading to cell death and cardiac remodeling

doi: 10.3389/fendo.2021.701246 Received 27 April 2021 Accepted 13 July 2021 Published 16 August 2021 Volume 12 - 2021 Edited by Veronica Vella, University of Catania, Italy Reviewed by Joseph A

doi: 10.1016/j.tube.2018.04.009 35 RandallPJHsuNJQuesniauxVRyffelBJacobsM