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The authors did observe some inter-metastatic heterogeneity, but these heterogeneous mutations were predicted to be nonfunctional

ROS encompass a range of highly reactive molecules, including singlet oxygen (1O2), hydrogen peroxide (H 2 O 2 ), and free radicals like the hydroxyl radical (OH) and superoxide anion (O2-)

It is crucial to note, however, that recent studies highlight significant systemic side effects of MCT4 inhibition due to its broad tissue expression, which may limit its clinical translational potential and necessitate the development of tissue-specific delivery strategies [138]

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coli was labelled with -alkynyl-palmitoyl CoA and incubated with NaOH (0.1 M) for one h, then subjected to click chemistry