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246 Numerous clinical trials have shown that huperzine A can improve cognitive function in people with dementia

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doi: 10.1038/nri.2017.7 61 LiX

The molecular sensor of this paradox is iron regulatory protein 1 (IRP1)

The misregulation of mTOR signaling was also observed in fragile X patients (Hoeffer et al., 2012), suggesting that mTOR could be a target or biomarker for treatment of fragile X syndrome